Effectivity of hemodialysis in acute gastrointestinal bleeding associated with dabigatran overdose
| Journal | Volume 80 - 2017 |
| Issue | Fasc.2 - Letters |
| Author(s) | C. Kilit, S. Erarslan, T. Pasali Kilit |
| Full article |
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| (1) Department of Cardiology, Dumlupinar University School of Medicine, Kutahya, Turkey ; (2) Department of Internal Medicine, Dumlupinar University, Kutahya Evliya Celebi Training and Research Hospital, Kutahya, Turkey ; (3) Department of Internal Medicine, Dumlupinar University School of Medicine, Kutahya, Turkey. |
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Novel oral anticoagulants (NOACs) have become available as alternatives for warfarin in patients with nonvalvular atrial fibrillation (AF). NOACs directly inhibit either factor IIa (dabigatran) or activated coagulation factor X. Limitations to the use of the NOACs include the lack of a reversal agent ; an inability to use the therapies in specific patient populations and a lack of available coagulation tests to quantify their effects. There are no published clinical trials or other high-quality evidence addressing the management of gastrointestinal (GI) bleeding on NOACs ; thus, most current recommendations are based on experts' opinions (1). |
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© Acta Gastro-Enterologica Belgica. PMID 29560702 |
